Doomination

From the letters page: Doomination comes from HardCorn and is built in Ren'Py. It is a trainer game built around harem, corruption and mind control, starring a male protagonist. Development is ongoing; the current version is 0.4.8. Available for Windows, Mac, Linux and Android, around 1.7 GB.

From the box: “Doomination is a comic-based parody point-and-click visual novel game. Doctor Doom, having been one step away from realizing his dream of becoming the ruler of the world, is now defeated and deprived of his powers and knowledge.”